glyoxalase

Noun. (biochemistry) Either of a pair of related thiol-dependent enzymes: ''glyoxalase І'', which catalyses the isomerisation of the spontaneously formed hemithioacetal adduct between GSH and 2-oxoaldehydes (such as methylglyoxal) into S-2-hydroxyacylglutathione; and ''glyoxalase ІІ'', which hydrolyses these thiolesters.

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This entry was last updated on RefTopia from its source on 3/20/2012.