1. (abbreviation) .  (biochemistry) arylsulfatase E, an enzyme, deficiencies in which are associated with abnormalities in cartilage and bone development.
  2. Noun.  (chiefly, UK) The buttocks.
  3. Noun.  (chiefly, UK) (not used in US, Canada) A stupid, mean or despicable person.
  4. Verb.  (slang, intransitive) To be silly, act stupid or mess around.
  5. Verb.  (slang) To have the effort to do something, to be bothered.

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This entry was last updated on RefTopia from its source on 3/20/2012.